ALETHEIA Safety API
1,879 compounds. 959 materials. 1,262 products. 2,325 fragrance ingredients. Regulatory classifications, exposure pathways, risk profiles, and 5D synthesis across IARC, EPA, EFSA, NTP, Prop 65, PubChem, and CompTox — delivered as clean JSON.
Compound, product, material, and fragrance lookup is free. No key required. Powers 7 GeodesicNexus safety apps.
Use Cases
Look up cosmetic or food ingredients by name or CAS number. Surface regulatory flags automatically.
The database has species-specific risk contexts for dogs and cats across hundreds of household chemicals.
Batch-check materials or compounds against IARC, EU REACH, EPA classifications before sourcing decisions.
Query regulatory disagreements across agencies. See where IARC, EPA, and EFSA diverge on the same compound.
Poison control lookups, exposure pathway data, and dose-response context for clinical tooling.
Aquatic life risk contexts, degradation data, and persistence classifications for environmental work.
Quick Start
The free endpoint returns a complete risk synthesis for any compound. No key required.
# Free — no API key needed
curl https://api.aletheia.holisticquality.io/api/compound/hq-c-org-000001?context=human_adult
# With API key — unlocks full database
curl -H "X-API-Key: aletheia_live_..." \
"https://api.aletheia.holisticquality.io/api/compounds?context=dog&risk_level=high"{
"hq_id": "hq-c-org-000001",
"name": "Glyphosate",
"context": "human_adult",
"risk_profile": {
"magnitude": {
"mean": 0.360,
"confidence_interval_95": [0.082, 0.638],
"source_positions": [
{ "source": "IARC", "value": 0.750, "weight": 0.680 },
{ "source": "EPA", "value": 0.150, "weight": 0.820 }
]
},
"consensus": {
"exists": false,
"disagreement_magnitude": 0.422
}
},
"interpretation": {
"summary": "Regulatory agencies show substantial disagreement..."
}
}
Individual lookups (/api/compound/:id, /api/product/:id,
/api/material/:id) and the fragrance catalog (/api/fragrance)
require no key, no account, no rate limit. That's 1,879 compounds, 1,262 products,
959 materials, and 2,325 fragrance ingredients available to anyone, permanently.
Paid tiers unlock lists, batch, comparison, and regulatory/exposure queries.
See what's included →
Base URL: https://api.aletheia.holisticquality.io
Free endpoints require no API key. Paid endpoints require a Developer ($29/mo) or Pro ($99/mo) key via X-API-Key header.
GET /api/compound/:id FREE
5D risk synthesis for a compound. Full regulatory consensus analysis.
Params: ?context=human_adult | ?all_contexts=true
GET /api/product/:id FREE
Full product detail — hazard summary, red/green flags, compounds of concern, materials, consumer guidance.
GET /api/material/:id FREE
Material detail — safety summary, compound linkage, thermal behavior, migration limits.
GET /api/compound/:id/contexts FREE
List all available risk contexts for a compound with descriptions.
GET /api/compound/:id/raw FREE
Raw compound JSON — full data file without synthesis processing.
GET /api/compound/cas/:cas FREE
Reverse lookup a compound by CAS registry number.
GET /api/fragrance FREE
Fragrance catalog — 2,325 ingredients across 29 chemical classes with safety priority scoring.
Sub-endpoints: /stats | /classes | /class/:name | /search?q=
GET /api/badge/:id FREE
Embeddable SVG risk badge for a compound. Drop into any page.
GET /api/health FREE
Health check. Also: /api/openapi — OpenAPI 3.1 spec.
GET /api/compounds API KEY
Paginated compound list with search, risk, type, and category filters.
Params: ?search= ?risk= ?context= ?type_filter= ?category_filter= ?page= ?limit=
GET /api/products API KEY
Paginated product list with search.
GET /api/materials API KEY
Paginated material list with search.
GET /api/compounds/batch?ids= API KEY
Fetch up to 20 compounds in a single request.
GET /api/compounds/compare?ids= API KEY
Side-by-side comparison of 2–5 compounds — risk deltas, LD50 ratios, regulatory agreement matrix, GHS diff.
GET /api/regulatory/:id API KEY
All regulatory classifications for a compound across IARC, EPA, EFSA, NTP, NIOSH, OSHA, EU, UNEP.
GET /api/regulatory/agencies /api/regulatory/by-agency/:agency API KEY
Agency list with counts, or all compounds classified by a specific agency.
GET /api/found-in/:id /api/found-in/categories /api/found-in/by-category/:cat API KEY
Exposure source data — where compounds are found, by category.
GET /api/keys/status API KEY
Your key's tier, daily usage, remaining requests.
POST /api/keys/recover FREE
Recover a lost API key. Body: {"email": "you@example.com"}. Rate limited to 3/hour.
Pass as ?context= query parameter. Not all compounds have all contexts — use /api/compound/:id/contexts to check. Aliases accepted (e.g. ?context=dog, ?context=pregnant, ?context=skin).
human_adult human_child human_pregnant human_elderly human_infantdog catexposure_ingestion exposure_inhalation exposure_dermal exposure_ocularaquatic_life terrestrial_wildlife pollinators{
"hq_id": "hq-c-org-000001",
"name": "Glyphosate",
"context": "human_adult",
"risk_profile": {
"magnitude": {
"mean": 0.360,
"std_dev": 0.284,
"confidence_interval_95": [0.082, 0.638],
"source_positions": [
{"source": "IARC", "value": 0.750, "weight": 0.680},
{"source": "EPA", "value": 0.150, "weight": 0.820}
]
},
"consensus": {
"exists": false,
"strength": 0.287,
"disagreement_magnitude": 0.422
}
},
"interpretation": {
"summary": "Regulatory agencies show substantial disagreement...",
"confidence_note": "High-quality evidence exists across sources..."
},
"sources": [...]
}Every source position exists in 5-dimensional risk space:
When agencies disagree, ALETHEIA doesn't pick sides. It shows you the full distribution.
Data source: safety.holisticquality.io — the HQ Safety Database powering this engine and 7 GeodesicNexus consumer safety apps.