ALETHEIA Safety API
1,183 compounds. 262 materials. 237 products. Regulatory classifications, exposure pathways, risk profiles, and synthesis across IARC, EPA, EFSA, and ATSDR — delivered as clean JSON.
Basic compound lookup is free. No key required.
Use Cases
Look up cosmetic or food ingredients by name or CAS number. Surface regulatory flags automatically.
The database has species-specific risk contexts for dogs and cats across hundreds of household chemicals.
Batch-check materials or compounds against IARC, EU REACH, EPA classifications before sourcing decisions.
Query regulatory disagreements across agencies. See where IARC, EPA, and EFSA diverge on the same compound.
Poison control lookups, exposure pathway data, and dose-response context for clinical tooling.
Aquatic life risk contexts, degradation data, and persistence classifications for environmental work.
Quick Start
The free endpoint returns a complete risk synthesis for any compound. No key required.
# Free — no API key needed
curl https://api.aletheia.holisticquality.io/api/compound/hq-c-0001?context=human_adult
# With API key — unlocks full database
curl -H "X-API-Key: aletheia_live_..." \
"https://api.aletheia.holisticquality.io/api/compounds?context=dog&risk_level=high"{
"hq_id": "hq-c-0001",
"name": "Glyphosate",
"context": "human_adult",
"risk_profile": {
"magnitude": {
"mean": 0.360,
"confidence_interval_95": [0.082, 0.638],
"source_positions": [
{ "source": "IARC", "value": 0.750, "weight": 0.680 },
{ "source": "EPA", "value": 0.150, "weight": 0.820 }
]
},
"consensus": {
"exists": false,
"disagreement_magnitude": 0.422
}
},
"interpretation": {
"summary": "Regulatory agencies show substantial disagreement..."
}
}
/api/compound/:id requires no key, no account, no rate limit.
That's 1,183 compounds available to anyone, permanently.
Paid tiers unlock the full query surface — paginated lists, batch lookups,
CAS search, regulatory filters, and exposure category queries.
See what's included →
Base URL: https://api.aletheia.holisticquality.io
GET /api/compound/:id FREE
Synthesize risk profile for a compound. No API key required.
Params: ?context=human_adult | ?all_contexts=true
GET /api/health FREE
Health check and system status.
GET /api/compounds API KEY
Paginated list of all compounds. Supports ?context=, ?risk_level=, ?limit=, ?offset= filters.
GET /api/compound/cas/:cas API KEY
Look up a compound by CAS registry number.
POST /api/compounds/batch API KEY
Fetch up to 50 compounds in a single request. Body: {"ids": ["hq-c-0001", "hq-c-0006"]}
GET /api/compound/:id/contexts API KEY
List all available risk contexts for a specific compound.
GET /api/contexts API KEY
List all valid contexts with descriptions and compound counts.
GET /api/regulatory/:id API KEY
All regulatory classifications for a compound across IARC, EPA, EFSA, NTP, NIOSH, OSHA, EU, UNEP.
GET /api/regulatory/agencies API KEY
All regulatory agencies in the database with classification counts.
GET /api/regulatory/by-agency/:agency API KEY
All compounds classified by a specific agency. Params: ?limit=100
GET /api/found-in/:id API KEY
All exposure categories and sources for a compound across 49 categories.
GET /api/found-in/categories API KEY
All exposure categories with compound counts.
GET /api/found-in/by-category/:category API KEY
All compounds found in a specific exposure category (drinking water, food, pet products, etc.).
GET /api/keys/status API KEY
Check your key's tier, daily usage, and remaining requests.
POST /api/keys/recover FREE
Recover a lost API key. Body: {"email": "you@example.com"}. Rate limited to 3/hour.
Pass as ?context= query parameter. Not all compounds have all contexts — use /api/compound/:id/contexts to check.
human_adult human_child human_pregnant human_elderlydog catexposure_dermal exposure_inhalation exposure_ingestion exposure_ocularaquatic_life terrestrial_wildlife pollinators{
"hq_id": "hq-c-0001",
"name": "Glyphosate",
"context": "human_adult",
"risk_profile": {
"magnitude": {
"mean": 0.360,
"std_dev": 0.284,
"confidence_interval_95": [0.082, 0.638],
"source_positions": [
{"source": "IARC", "value": 0.750, "weight": 0.680},
{"source": "EPA", "value": 0.150, "weight": 0.820}
]
},
"consensus": {
"exists": false,
"strength": 0.287,
"disagreement_magnitude": 0.422
}
},
"interpretation": {
"summary": "Regulatory agencies show substantial disagreement...",
"confidence_note": "High-quality evidence exists across sources..."
},
"sources": [...]
}Every source position exists in 5-dimensional risk space:
When agencies disagree, ALETHEIA doesn't pick sides. It shows you the full distribution.
Data source: safety.holisticquality.io — the HQ Safety Database powering this engine.