How developers integrate chemical safety intelligence into their products
ALETHEIA serves 1,879 compounds across 19 exposure contexts, with regulatory data from 202 agencies. Here's how teams are using it.
Screen ingredients against EU Cosmetics Regulation, IFRA standards, and FDA guidelines before they reach the lab bench. ALETHEIA's multi-context risk synthesis lets formulators evaluate a single ingredient across every relevant exposure scenario simultaneously.
Check if a preservative like methylisothiazolinone is safe across all contexts before launch. The API returns the full regulatory distribution — EU banned in leave-on products, FDA permits with limits, IFRA restricts concentration — so your formulation team sees the complete picture, not a collapsed yes/no.
GET /api/compound/cas/2682-20-4?context=dermal_contact
Verify FDA GRAS status, EU food additive approvals, and contaminant limits in a single API call. Food manufacturers and ingredient suppliers use ALETHEIA to cross-reference regulatory positions before formulation decisions.
Verify a food-grade colorant like tartrazine (FD&C Yellow #5) against FDA and EU simultaneously. ALETHEIA shows where agencies agree (permitted with limits) and where they diverge (ADI thresholds, labeling requirements).
GET /api/compound/cas/1934-21-0?context=oral_ingestion
Audit ingredient lists against CPSC requirements, EPA registrations, and California Prop 65 in bulk. ALETHEIA covers 1,262 products with formulation data and material composition, so compliance teams can screen entire product lines programmatically.
Audit a cleaning product's full ingredient list in one batch API call. The response flags Prop 65 listed compounds, EPA-restricted substances, and any ingredients where regulatory agencies disagree on risk classification.
POST /api/compounds/batch { "cas_numbers": ["111-76-2", "68-12-2", "110-54-3"] }
Compare regulatory positions across 202 agencies worldwide. When agencies disagree, ALETHEIA shows the full distribution — mean risk, standard deviation, confidence intervals — instead of hiding the uncertainty behind a single score.
Track regulatory changes for your compound portfolio. Set up a watchlist for your key ingredients, subscribe to changelog updates via webhooks, and get notified when any agency revises a classification that affects your products.
POST /api/watchlist { "cas": "1071-83-6", "label": "Glyphosate monitoring" }
Access PBT (persistent, bioaccumulative, toxic) classification, environmental fate data, and PFAS tracking for environmental compliance. ALETHEIA includes 46 PFAS compounds with detailed profiles covering biodegradation, bioaccumulation, and persistence metrics.
Screen a discharge list for PBT characteristics and PFAS presence. The environmental context applies aquatic toxicity weighting and flags compounds with persistence concerns, bioaccumulation factors, or PFAS classification.
GET /api/compound/cas/335-67-1?context=environmental
Species-specific toxicity matters. An ingredient safe for humans can be lethal to cats. ALETHEIA provides dedicated contexts for companion animals and covers 63 pet products with full compound composition data.
Check if tea tree oil (melaleuca) — popular in human products — is safe for cats. ALETHEIA's cat-specific context flags the well-documented feline hepatotoxicity that a human-only risk assessment would miss entirely.
GET /api/compound/cas/68647-73-4?context=domestic_cat
Free tier: 500 requests/day, no API key required.
7-day Developer trial: 10,000 requests/day, no credit card.